Phosphate excess and progressive renal failure: The precipitation-calcification hypothesis
نویسندگان
چکیده
منابع مشابه
Role of calcium-phosphate product and bone-associated proteins on vascular calcification in renal failure.
Cardiovascular events are the most frequent cause of death in patients with chronic renal failure (1–2). Heterotopic calcification of blood vessel walls occurs frequently with advanced age, atherosclerosis, and diabetes mellitus (3). In chronic renal failure, autopsy (4–5) and clinical investigations (6) have documented a higher prevalence of coronary plaques in dialyzed patients compared with ...
متن کاملIdentifying and slowing progressive chronic renal failure.
OBJECTIVE To help inform primary care physicians about how to identify and slow progressive chronic renal failure. QUALITY OF EVIDENCE The National Library of Medicine (1996 to 2000) was searched using PubMed with search terms pertinent to studies on identification, course, and management of chronic renal failure. References in retrieved papers and older literature known to the authors supple...
متن کاملVascular Calcification in Chronic Renal Failure
Accelerated atherosclerotic plaque calcification and extensive medial calcifications are common and highly detrimental complications of chronic kidney disease. Valid murine models have been developed to investigate both pathologically distinguishable complications, which allow for better insight into the cellular mechanisms underlying these vascular pathologies and evaluation of compounds that ...
متن کاملVascular calcification in chronic renal failure.
The prevalence and extent of vascular calcification (VC) increases rapidly with time on dialysis. There is increasing evidence that medial calcification of conduit arteries, without intimal disease, is associated with important abnormalities of vascular compliance and increased risk of cardiovascular death. Coronary artery calcification is also common in end-stage renal disease, but further res...
متن کاملMitral anular calcification in chronic renal failure.
In order to determine the incidence and pathogenesis of mitral anular calcification (MAC) in chronic renal failure, we analyzed biochemical, hemodynamic and echocardiographic data in 168 patients on long-term hemodialysis. Mitral anular calcification is more common in patients with chronic renal failure than in other patients of similar age. Its pathogenesis appears to be due to abnormal calciu...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1989
ISSN: 0085-2538
DOI: 10.1038/ki.1989.281